MOTS-C 5mg Peptide Lyophilized Powder C₈₉H₁₅₂N₂₄O₂₂S₂

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Item number: 1627580‑64‑6

Molecular Formula: C₁₀₁H₁₅₂N₂₈O₂₂S₂

Molecular Weight: 2174.62 g/mol

CAS Number: 1627580‑64‑6

What is MOTS-C

  • A mitochondrial‑derived peptide (MDP) encoded within the 12S rRNA region of mitochondrial DNA.

  • Consists of 16 amino acids.

  • Functions as a metabolic regulator and “mitohormone” that helps cells adapt to stress.

 

🔬 How MOTS‑c Works (Research Context)

1. AMPK Pathway Activation

MOTS‑c inhibits part of the folate cycle, which leads to AMPK activation, a master regulator of cellular energy and metabolism.

2. Nuclear Translocation Under Stress

During metabolic stress, MOTS‑c moves from mitochondria to the nucleus, where it binds transcription factors like NRF2 and ATF1/ATF7 to regulate stress‑response genes.

3. Metabolic Regulation

Research highlights roles in:

  • glucose utilisation

  • fat oxidation

  • insulin sensitivity

  • energy homeostasis

 

🧪 Key Research Findings

  • Improved insulin sensitivity (~30% in some models)

  • Enhanced glucose metabolism and tolerance

  • Increased exercise performance (12–15% in animal studies)

  • Potential lifespan extension in mice (6.4% median increase)

  • Supports metabolic efficiency and mitochondrial function

These findings come from preclinical and laboratory research — not approved medical use.

Reconstitute with BAC's Water Only
When reconstituting peptides, it is crucial to use bacteriostatic water (BAC) to ensure sterility and safety.


BAC water contains 0.9% Benzyl Alcohol and is bacteria-proof, making it the preferred choice for reconstitution.

This method helps preserve the integrity of the peptide and prevents contamination.


To reconstitute a peptide blend, follow these steps:
Disinfect both vials and the stoppers with alcohol wipes.


Measure the required amount of BAC water based on the dosage.
Mix the peptide powder with the measured BAC water in a sterile syringe.


Inject the solution into the vial and refrigerate at 2–8°C, protected from light.


Use the reconstituted solution within 4 weeks for best potency and safety.


Always consult with a healthcare provider before starting any new treatment, including peptide reconstitution.

Legal and Safety Information;

Quantum Peptides products are provided exclusively for laboratory research and educational use.

They are not approved for human or veterinary applications.

These materials are not intended to diagnose, treat, cure, or prevent any medical condition.

All use must adhere to applicable laws and regulatory requirements.